Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29814900 | 0.89 | KMT2A (0.43) | LMNAKMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL27002004 | 0.87 | SMN1; SMN2 (0.46) | LMNAKMT2AMEN1SMN1; SMN2NSD2 | |
| SCHEMBL29814853 | 0.82 | MEN1 (0.47) | LMNAKMT2AMEN1TSHRHTT | |
| SCHEMBL29279571 | 0.76 | MAPT (0.39) | LMNAKMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL27002000 | 0.76 | HTR2A (0.48) | — | |
| SCHEMBL27002165 | 0.76 | KMT2A (0.45) | LMNAKMT2AMEN1SMN1; SMN2NSD2 | |
| SCHEMBL14811705 | 0.76 | SMN1; SMN2 (0.62) | LMNAKMT2ASMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL14495036 | 0.75 | NQO2 (0.45) | MTNR1AMTNR1BNQO2IDO1SUV39H2 | |
| SCHEMBL24163782 | 0.75 | HTR2A (0.57) | KMT2ASMN1; SMN2MTNR1AMTNR1BIDO1 | |
| SCHEMBL29814777 | 0.75 | NQO2 (0.48) | SMN1; SMN2NQO2IDO1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642379-A | Phenylalkylamines and methods of making and using the same | 吉尔伽美什制药公司 | 2024-03-01 | — | — | CN | disclosed |
| EP-4305019-A1 | PHENALKYLAMINES AND METHODS OF MAKING AND USING THE SAME | Gilgamesh Pharmaceuticals, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022192781-A1 | PHENALKYLAMINES AND METHODS OF MAKING AND USING THE SAME | GILGAMESH PHARMACEUTICALS, INC. (US) | 2022-09-15 | — | — | WO | disclosed |