Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27002043 | 0.84 | USP2 (0.43) | LMNAKMT2ACNR2CA1CA2 | |
| SCHEMBL29814900 | 0.83 | KMT2A (0.43) | MEN1LMNATSHRKMT2AHTT | |
| SCHEMBL29279529 | 0.82 | LMNA (0.43) | MEN1LMNATSHRKMT2AHTT | |
| SCHEMBL31432851 | 0.75 | CA12 (0.64) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL903446 | 0.75 | CA12 (0.64) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL23684682 | 0.75 | CACNA1H (0.42) | MEN1KMT2ACA1CA2DRD2 | |
| SCHEMBL14823576 | 0.74 | MAPK1 (0.41) | CA1CA2HTTDRD2 | |
| SCHEMBL69181 | 0.73 | MTNR1A (0.59) | LMNATSHRCA1CA2 | |
| SCHEMBL29998779 | 0.73 | MTNR1A (0.59) | LMNATSHRCA1CA2 | |
| SCHEMBL29814777 | 0.73 | NQO2 (0.48) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4305019-A1 | PHENALKYLAMINES AND METHODS OF MAKING AND USING THE SAME | Gilgamesh Pharmaceuticals, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022192781-A1 | PHENALKYLAMINES AND METHODS OF MAKING AND USING THE SAME | GILGAMESH PHARMACEUTICALS, INC. (US) | 2022-09-15 | — | — | WO | disclosed |