Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29279556 | 0.81 | TAAR1 (0.49) | HTR2ATAAR1 | |
| SCHEMBL25236494 | 0.78 | HTR2A (0.59) | HTR2AHTR2CTAAR1 | |
| SCHEMBL16428699 | 0.77 | TAAR1 (0.61) | HTR2AHTR2CTAAR1ALDH1A1KDM4E | |
| SCHEMBL29279526 | 0.76 | HTR2A (0.50) | HTR2AHTR2CTAAR1 | |
| SCHEMBL29279543 | 0.76 | TAAR1 (0.42) | HTR2AHTR2CTAAR1AR | |
| SCHEMBL27002100 | 0.75 | HTR2A (0.56) | HTR2AHTR2CIMPDH2ALDH1A1 | |
| SCHEMBL29279597 | 0.75 | HTR2A (0.49) | HTR2AHTR2CTAAR1 | |
| SCHEMBL27002157 | 0.75 | CYP3A4 (0.67) | HTR2AHTR2CIMPDH2ALDH1A1AR | |
| SCHEMBL29171822 | 0.74 | TAAR1 (0.39) | HTR2AHTR2CTAAR1KDM4E | |
| SCHEMBL27187479 | 0.74 | IMPDH2 (0.41) | HTR2AHTR2CTAAR1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642379-A | Phenylalkylamines and methods of making and using the same | 吉尔伽美什制药公司 | 2024-03-01 | — | — | CN | disclosed |