Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745911 | 0.91 | PPARA (0.50) | PPARALMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30745891 | 0.90 | PPARA (0.56) | PPARALMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL29279812 | 0.90 | PPARA (0.56) | PPARALMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30745898 | 0.88 | MAPT (0.41) | PPARALMNASMN1; SMN2MAPTTP53 | |
| SCHEMBL30745858 | 0.88 | EPHX2 (0.51) | TRPV1 | |
| SCHEMBL29279995 | 0.86 | TRPV1 (0.47) | PPARALMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30745878 | 0.86 | TRPV1 (0.47) | PPARALMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL29279854 | 0.82 | TRPV1 (0.47) | PPARALMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL29279870 | 0.80 | MEN1 (0.56) | LMNASMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL29279805 | 0.80 | MAOB (0.54) | PPARALMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117682973-A | Sulfonamide compound and medical application thereof | 中国药科大学 | 2024-03-12 | — | — | CN | disclosed |