⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143 | 0.76 | HTR2C (0.36) | — | |
| SCHEMBL454140 | 0.76 | RYR2 (0.31) | — | |
| SCHEMBL2514824 | 0.76 | RYR2 (0.31) | — | |
| SCHEMBL452312 | 0.76 | SIGMAR1 (0.33) | — | |
| SCHEMBL7280713 | 0.73 | RYR2 (0.33) | — | |
| SCHEMBL884370 | 0.73 | TSHR (0.42) | — | |
| SCHEMBL832046 | 0.72 | RYR2 (0.53) | — | |
| SCHEMBL2873 | 0.67 | RYR2 (0.31) | — | |
| SCHEMBL9501242 | 0.67 | RYR2 (0.39) | — | |
| SCHEMBL156105 | 0.67 | RYR2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 17682 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240115564-A1 | HTR1F ANTAGONISTS FOR IMPROVEMENT OF BETA CELL SURVIVAL AND FUNCTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-04-11 | — | — | US | claimed |
| EP-4337639-A1 | NAMPT INHIBITORS AND USES THEREOF | Remedy Plan, Inc. (US) | 2024-03-20 | — | — | EP | claimed |
| CN-117597336-A | Halogen substituted amino aza-heteroaryl compounds as inhibitors of hematopoietic progenitor kinase 1 (HPK 1) | 安大略省癌症研究所(OICR) | 2024-02-23 | — | — | CN | claimed |
| EP-4301816-A1 | COATING COMPOSITIONS COMPRISING A POLYSULFIDE CORROSION INHIBITOR | PRC-Desoto International, Inc. (US) | 2024-01-10 | — | — | EP | claimed |
| CN-117377727-A | Coating composition comprising polysulfide corrosion inhibitor | PRC-迪索托国际公司 | 2024-01-09 | — | — | CN | claimed |
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | claimed |
| US-11839613-B2 | Pyrimidine derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-12-12 | — | — | US | claimed |
| CN-116157397-A | Heterocyclylpyridines as novel fungicides | 拜耳公司 | 2023-05-23 | — | — | CN | claimed |
| CN-115803317-A | Azabicyclo (thio) amides as fungicidal compounds | 拜耳作物科学股份公司 | 2023-03-14 | — | — | CN | claimed |
| US-11584745-B2 | Aromatic heterocyclic compound, intermediate thereof, preparation method therefor, and pharmaceutical composition and use thereof | SHANGHAI YINGLI PHARMACEUTICAL CO., LTD (CN) | 2023-02-21 | — | — | US | claimed |
| US-4824834-A | TREATING GOUT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-04-25 | — | — | US | claimed |
| EP-0269859-A2 | Pyrazolotriazine compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-08 | — | — | EP | claimed |
| CN-87107217-A | Method for preparation of pyrazolotriazine compounds | — | 1988-05-11 | — | — | CN | claimed |
| US-4638000-A | HYPOTENSIVES, ANGIOTENSIN INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-01-20 | — | — | US | claimed |
| EP-0200455-A2 | 2,3,4,5-tetrahydro-1H-3-benzazepines substituted in position 5 | NOVO NORDISK A/S (DK) | 1986-11-05 | — | — | EP | claimed |
| US-4548932-A | ANGIOTENSIN INHIBITOR, HYPOTENSIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-10-22 | — | — | US | claimed |
| US-4460594-A | CENTRAL NERVOUS SYSTEM DISORDERS | BEECHAM GROUP P.L.C. (GB) | 1984-07-17 | — | — | US | claimed |
| US-4430341-A | INSECTICIDES, MITICIDES | UNION CARBIDE CORPORATION (US) | 1984-02-07 | — | — | US | claimed |
| EP-0077607-A1 | N-substituted 3-aryl piperidines and derivatives thereof | BEECHAM GROUP PLC (GB) | 1983-04-27 | — | — | EP | claimed |
| US-4201786-A | INSECTICIDES, MITICIDES | UNION CARBIDE CORPORATION (US) | 1980-05-06 | — | — | US | claimed |