SCHEMBL29280279

SCHEMBL29280279

NCCC(N)(n1ccnc1)n1ccnc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
TBXAS1 P24557 5/20 0.36
CYP19A1 P11511 5/20 0.33
CYP17A1 P05093 3/20 0.32
NR1I2 O75469 2/20 0.30
ADORA3 P0DMS8 2/20 0.30
TBXA2R P21731 2/20 0.30
CCKBR P32239 2/20 0.30
OPRK1 P41145 2/20 0.30
SLC6A3 Q01959 2/20 0.30
KCNH2 Q12809 2/20 0.30
NR1H4 Q96RI1 2/20 0.30
MLNR O43193 1/20 0.30
NFKB1 P19838 2/20 0.30
MEN1 O00255 1/20 0.30
SLC22A1 O15245 1/20 0.30
KCNN4 O15554 1/20 0.30
GMNN O75496 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14415940 0.78 TBXAS1 (0.53) CYP11B1CYP11B2TBXAS1CYP19A1CYP17A1
SCHEMBL13919194 0.69 TBXAS1 (0.45) CYP11B1CYP11B2TBXAS1CYP19A1CYP17A1
SCHEMBL27667254 0.69 CYP11B1 (0.42) CYP11B1CYP11B2TBXAS1CYP19A1CYP17A1
SCHEMBL10654788 0.69
SCHEMBL4066404 0.69
SCHEMBL1814815 0.68 CYP17A1 (0.42) CYP11B1CYP11B2TBXAS1CYP19A1CYP17A1
SCHEMBL9023298 0.68 CYP17A1 (0.32) TBXAS1CYP17A1
Bromide SCHEMBL28276997 0.67 CYP11B1 (0.41) CYP11B1CYP11B2TBXAS1CYP19A1CYP17A1
SCHEMBL21392728 0.67 TBXAS1 (0.50) CYP11B1CYP11B2TBXAS1CYP19A1CYP17A1
SCHEMBL7771361 0.67 TBXAS1 (0.43) CYP11B1CYP11B2TBXAS1CYP19A1CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117720559-A Keggin type polyacid-based Cu (II) coordination ion crystal and preparation method thereof 北京化工大学 2024-03-19 CN claimed
CN-117720559-A Keggin type polyacid-based Cu (II) coordination ion crystal and preparation method thereof 北京化工大学 2024-03-19 CN disclosed