Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 17/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 16/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25221624 | 0.88 | PRMT5 (0.58) | PRMT5WDR77 | |
| SCHEMBL30833175 | 0.88 | PRMT5 (0.43) | PRMT5WDR77 | |
| SCHEMBL29735261 | 0.83 | PRMT5 (0.59) | PRMT5WDR77 | |
| SCHEMBL23087822 | 0.83 | PRMT5 (0.59) | PRMT5WDR77 | |
| SCHEMBL30429824 | 0.82 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL23087167 | 0.80 | PRMT5 (0.55) | PRMT5WDR77 | |
| SCHEMBL29735130 | 0.80 | PRMT5 (0.55) | PRMT5WDR77 | |
| SCHEMBL25216634 | 0.78 | PRMT5 (0.50) | PRMT5WDR77 | |
| SCHEMBL23087746 | 0.78 | PRMT5 (0.72) | PRMT5WDR77 | |
| SCHEMBL29735240 | 0.78 | PRMT5 (0.72) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117730075-A | Pyrazole derivative, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2024-03-19 | — | — | CN | disclosed |