Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 20/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 14/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25208948 | 0.88 | PRMT5 (0.58) | PRMT5WDR77 | |
| SCHEMBL29280298 | 0.88 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL30429567 | 0.85 | PRMT5 (0.56) | PRMT5WDR77 | |
| SCHEMBL25221624 | 0.76 | PRMT5 (0.58) | PRMT5WDR77 | |
| SCHEMBL30429824 | 0.73 | PRMT5 (0.46) | PRMT5WDR77 | |
| SCHEMBL29280294 | 0.72 | PRMT5 (0.63) | PRMT5WDR77 | |
| SCHEMBL25581297 | 0.72 | PRMT5 (0.36) | PRMT5WDR77 | |
| SCHEMBL25263666 | 0.72 | PRMT5 (0.79) | PRMT5WDR77 | |
| SCHEMBL25216634 | 0.71 | PRMT5 (0.50) | PRMT5WDR77 | |
| SCHEMBL23087822 | 0.71 | PRMT5 (0.59) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117730075-A | Pyrazole derivative, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2024-03-19 | — | — | CN | disclosed |