Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTPRCAP | Q14761 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29280310 | 1.00 | L3MBTL1 (0.37) | L3MBTL1PTPRCAPDYRK1ACHRM5CHRM3 | |
| SCHEMBL25302799 | 0.71 | L3MBTL1 (0.33) | L3MBTL1CHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL25302800 | 0.71 | L3MBTL1 (0.33) | L3MBTL1CHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL21451584 | 0.70 | CYP3A4 (0.32) | — | |
| SCHEMBL30068675 | 0.69 | L3MBTL1 (0.34) | L3MBTL1CHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL25838285 | 0.69 | CHRM2 (0.37) | L3MBTL1CHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL22040163 | 0.68 | EED (0.48) | L3MBTL1CHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL30068946 | 0.66 | CHRM5 (0.40) | L3MBTL1CHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL16309083 | 0.64 | L3MBTL1 (0.46) | L3MBTL1CHRM5CHRM3CHRM2CHRM1 | |
| SCHEMBL29150759 | 0.64 | L3MBTL1 (0.46) | L3MBTL1CHRM5CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925360-B | 1-heterocyclylisochromanyl compounds and analogs for the treatment of CNS disorders | 赛诺维信制药公司 | 2024-03-22 | — | — | CN | disclosed |