Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL637946 | 0.84 | L3MBTL1 (0.60) | KDM4EALDH1A1LMNAHPGDMAPT | |
| SCHEMBL638412 | 0.83 | L3MBTL1 (0.63) | KDM4EALDH1A1LMNAHPGDMAPT | |
| SCHEMBL24951311 | 0.81 | HPGD (0.48) | KDM4EALDH1A1LMNAHPGDMAPT | |
| SCHEMBL639370 | 0.81 | KDM4E (0.64) | KDM4EALDH1A1LMNAHPGDMAPT | |
| SCHEMBL16695835 | 0.78 | MAOB (0.52) | KDM4EALDH1A1LMNAHPGDMAPT | |
| SCHEMBL18090295 | 0.75 | HRH4 (0.43) | KDM4EALDH1A1LMNAHPGDMAPT | |
| SCHEMBL14554786 | 0.74 | SCN9A (0.44) | KDM4EALDH1A1LMNAHPGDMAPT | |
| SCHEMBL1083907 | 0.73 | SMAD3 (0.74) | ALDH1A1MAPTL3MBTL1TSHRGAA | |
| SCHEMBL639540 | 0.73 | GBA1 (0.66) | ACHEMEN1KMT2AGBA1TLR7 | |
| SCHEMBL31133354 | 0.73 | GBA1 (0.66) | ACHEMEN1KMT2AGBA1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4377305-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | BenevolentAI Cambridge Limited (GB) | 2024-06-05 | — | — | EP | disclosed |
| CN-117751107-A | Organic pyridine-pyrazole compounds and uses thereof | 博善人工智能剑桥有限公司 | 2024-03-22 | — | — | CN | disclosed |
| WO-2023007184-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |