Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.48 |
| ▸ | GLP1R | P43220 | 8/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20797921 | 0.89 | FOLH1 (0.48) | SLC6A5FOLH1GLP1RC3AR1SLC15A2 | |
| SCHEMBL19019936 | 0.89 | FOLH1 (0.48) | SLC6A5FOLH1GLP1RC3AR1SLC15A2 | |
| SCHEMBL6974284 | 0.89 | FOLH1 (0.50) | SLC6A5FOLH1GLP1RC3AR1SLC15A2 | |
| SCHEMBL450379 | 0.89 | FOLH1 (0.50) | SLC6A5FOLH1GLP1RC3AR1SLC15A2 | |
| SCHEMBL25309372 | 0.88 | FOLH1 (0.47) | SLC6A5FOLH1GLP1RC3AR1SLC15A2 | |
| SCHEMBL30914214 | 0.88 | FOLH1 (0.47) | SLC6A5FOLH1GLP1RC3AR1SLC15A2 | |
| SCHEMBL7135222 | 0.88 | FOLH1 (0.47) | SLC6A5FOLH1GLP1RC3AR1SLC15A2 | |
| SCHEMBL25309366 | 0.88 | FOLH1 (0.47) | SLC6A5FOLH1GLP1RC3AR1SLC15A2 | |
| SCHEMBL21443609 | 0.85 | GLP1R (0.45) | SLC6A5FOLH1GLP1RC3AR1SLC15A2 | |
| SCHEMBL14959535 | 0.85 | SLC6A5 (0.52) | SLC6A5GLP1RNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871403-B1 | COMPOSITIONS AND METHODS FOR THE CONTROL, PREVENTION AND TREATMENT OF EATING DISORDERS | AMYLIN PHARMACEUTICALS INC (US) | 2010-09-08 | — | — | EP | disclosed |