Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23991558 | 1.00 | USP30 (0.36) | USP30AAK1MEN1KMT2ABUB1 | |
| SCHEMBL27174548 | 0.84 | MAPK1 (0.33) | — | |
| SCHEMBL27174551 | 0.84 | MAPK1 (0.33) | — | |
| SCHEMBL29524125 | 0.83 | SMYD2 (0.35) | USP30MEN1KMT2A | |
| SCHEMBL29035344 | 0.83 | SMYD2 (0.35) | USP30MEN1KMT2A | |
| SCHEMBL30301912 | 0.83 | SMYD2 (0.35) | USP30MEN1KMT2A | |
| SCHEMBL19078451 | 0.82 | USP30 (0.38) | USP30AAK1MEN1KMT2ABUB1 | |
| SCHEMBL16339902 | 0.81 | USP30 (0.40) | USP30AAK1BUB1DGAT1PTPN1 | |
| SCHEMBL28648680 | 0.81 | USP30 (0.40) | USP30AAK1BUB1DGAT1PTPN1 | |
| SCHEMBL16339903 | 0.81 | USP30 (0.40) | USP30AAK1BUB1DGAT1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813298-A | Imidazole indazole compounds as JAK inhibitors | 施万生物制药研发IP有限责任公司 | 2024-04-02 | — | — | CN | disclosed |