Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29524125 | 1.00 | SMYD2 (0.35) | SMYD2USP30MEN1KMT2AALDH1A1 | |
| SCHEMBL30301912 | 1.00 | SMYD2 (0.35) | SMYD2USP30MEN1KMT2AALDH1A1 | |
| SCHEMBL25362860 | 0.90 | SMYD2 (0.37) | SMYD2ROCK1SMN1; SMN2 | |
| SCHEMBL27174566 | 0.90 | SMYD2 (0.37) | SMYD2ROCK1SMN1; SMN2 | |
| SCHEMBL25362863 | 0.90 | SMYD2 (0.37) | SMYD2ROCK1SMN1; SMN2 | |
| SCHEMBL23991558 | 0.83 | USP30 (0.36) | USP30MEN1KMT2A | |
| SCHEMBL29280770 | 0.83 | USP30 (0.36) | USP30MEN1KMT2A | |
| SCHEMBL29035259 | 0.80 | MEN1 (0.37) | SMYD2USP30MEN1KMT2AGPR119 | |
| SCHEMBL29035255 | 0.80 | MEN1 (0.37) | SMYD2USP30MEN1KMT2AGPR119 | |
| SCHEMBL13655737 | 0.78 | RORC (0.39) | USP30MEN1KMT2AABCB1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813298-A | Imidazole indazole compounds as JAK inhibitors | 施万生物制药研发IP有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-116437913-A | Pharmaceutical compounds for treating complement-mediated disorders | 艾其林医药公司 | 2023-07-14 | — | — | CN | disclosed |