Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 8/20 | 0.44 |
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29280926 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL30840071 | 0.83 | MEN1 (0.55) | KDM4EALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL29280894 | 0.83 | MEN1 (0.55) | KDM4EALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL29280918 | 0.83 | GABRA5 (0.47) | KDM4EALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL29280913 | 0.81 | CACNA1I (0.52) | KDM4EALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL29280878 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL30843813 | 0.80 | HTR2A (0.44) | KDM4EALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL29280920 | 0.80 | HTR2A (0.44) | KDM4EALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL29280933 | 0.80 | F10 (0.51) | KDM4EALDH1A1TSHRHTTSMN1; SMN2 | |
| SCHEMBL29280915 | 0.80 | HTR2A (0.61) | KDM4EHTR2AHTR2CKCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820199-A | Amide compound and application thereof in preparation of Sigma2 and 5HT2A inhibitors | 瀚远医药有限公司 | 2024-04-05 | — | — | CN | disclosed |