Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 9/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29280893 | 0.78 | CCR5 (0.49) | KCNH2GPR119CCR5 | |
| SCHEMBL5860907 | 0.78 | CCR5 (0.56) | CHRM1CCR5SIGMAR1 | |
| SCHEMBL29280907 | 0.78 | SMN1; SMN2 (0.48) | KCNH2GPR119CCR5 | |
| SCHEMBL29280887 | 0.78 | KCNH2 (0.45) | KCNH2GPR119CCR5 | |
| SCHEMBL29280890 | 0.77 | CCR5 (0.52) | KCNH2GPR119CCR5SIGMAR1 | |
| SCHEMBL29280944 | 0.77 | CCR5 (0.51) | KCNH2GPR119CCR5SIGMAR1 | |
| SCHEMBL6701738 | 0.75 | CCR5 (0.55) | CHRM1KCNH2GPR119CCR5SLC6A2 | |
| SCHEMBL29208060 | 0.74 | BRD4 (0.38) | — | |
| SCHEMBL29208108 | 0.74 | HTR2A (0.40) | KCNH2USP30 | |
| SCHEMBL2404000 | 0.74 | CCR5 (0.44) | KCNH2GPR119CCR5SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820199-A | Amide compound and application thereof in preparation of Sigma2 and 5HT2A inhibitors | 瀚远医药有限公司 | 2024-04-05 | — | — | CN | disclosed |