Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 20/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 7/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 7/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 7/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.84 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.80 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29281228 | 0.94 | TGFBR1 (1.00) | TGFBR1CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL29281278 | 0.91 | TGFBR1 (1.00) | TGFBR1CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL29281255 | 0.89 | TGFBR1 (1.00) | TGFBR1CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL29281268 | 0.87 | TGFBR1 (1.00) | TGFBR1CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL30855631 | 0.86 | TGFBR1 (1.00) | TGFBR1CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL29281215 | 0.86 | TGFBR1 (1.00) | TGFBR1CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL29281250 | 0.85 | TGFBR1 (1.00) | TGFBR1CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL30855668 | 0.85 | TGFBR1 (1.00) | TGFBR1CYP2D6CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL29281258 | 0.83 | TGFBR1 (0.89) | TGFBR1CYP2D6CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL29281233 | 0.81 | TGFBR1 (1.00) | TGFBR1CYP2D6CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881669-A | Condensed ring heteroaryl compounds and uses thereof | 比西切姆有限公司 | 2024-04-12 | — | — | CN | disclosed |