Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312915 | 0.70 | CCR4 (0.55) | CCR4KAT2BTP53TRPV1 | |
| SCHEMBL19945232 | 0.69 | PDCD1 (0.52) | KDRCCR4TP53FAAHJAK2 | |
| SCHEMBL29282122 | 0.68 | KDR (0.40) | KDRCCR4FAAHJAK2JAK3 | |
| SCHEMBL24312500 | 0.68 | CCR4 (0.38) | KDRCCR4TP53FAAHJAK2 | |
| SCHEMBL13707016 | 0.68 | CCR4 (0.53) | CCR4TP53TRPV1 | |
| SCHEMBL31130330 | 0.68 | CCR4 (0.50) | KDRCCR4TP53SYKTRPV1 | |
| SCHEMBL11806943 | 0.68 | TDP1 (0.44) | KDM1AKDM4ELMNATSHRHTT | |
| SCHEMBL256207 | 0.67 | CYP11B1 (0.43) | KDRCCR4TP53CYP1A2NPC1 | |
| SCHEMBL25628273 | 0.67 | KDM4E (0.38) | KDRCCR4IRAK4FAAHJAK2 | |
| SCHEMBL15077331 | 0.66 | CCR4 (0.39) | KDRCCR4FAAHSYKCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986241-A | Biphenyl derivative, pharmaceutical composition and application thereof | 武汉睿健医药科技有限公司 | 2024-05-07 | — | — | CN | disclosed |