Pyridine

Pyridine

SCHEMBL29282948

c1ccc(N(c2ccccc2)c2ccccc2)cc1.c1ccncc1.c1ccncc1.c1ccncc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.50
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TSHR P16473 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
NOTUM Q6P988 1/20 0.43
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
CRHBP P24387 1/20 0.41
ATM Q13315 1/20 0.41
CRHR2 Q13324 1/20 0.41
TLR9 Q9NR96 1/20 0.41
KCNA5 P22460 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL27549903 1.00 TDP1 (0.50) TDP1ALDH1A1KDM4EL3MBTL1TSHR
Pyrazine SCHEMBL28194265 0.92 ALDH1A1 (0.52) TDP1ALDH1A1KDM4EL3MBTL1TSHR
SCHEMBL7906546 0.89 ALDH1A1 (0.50) TDP1ALDH1A1KDM4EL3MBTL1TSHR
SCHEMBL16484729 0.89 ALDH1A1 (0.50) TDP1ALDH1A1KDM4EL3MBTL1TSHR
Anthracene SCHEMBL27949433 0.89 ALDH1A1 (0.41) TDP1ALDH1A1KDM4EL3MBTL1TSHR
Pyridine SCHEMBL29266075 0.87 ALDH1A1 (0.40) TDP1ALDH1A1KDM4EL3MBTL1TSHR
Pyridine SCHEMBL29267720 0.87 KMT2A (0.42) TDP1ALDH1A1KDM4EL3MBTL1TSHR
Pyridazine SCHEMBL28435293 0.83 ALDH1A1 (0.50) TDP1ALDH1A1KDM4EL3MBTL1TSHR
SCHEMBL6328963 0.82 KCNA5 (0.53) TDP1ALDH1A1KDM4EL3MBTL1TSHR
Bromide SCHEMBL28357041 0.82 NOTUM (0.64) TDP1ALDH1A1KDM4EL3MBTL1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063786-A Novel MOF material and application thereof in lithium ion battery cathode 苏州芼孚士科技有限公司 2024-05-24 CN claimed
CN-118063786-A Novel MOF material and application thereof in lithium ion battery cathode 苏州芼孚士科技有限公司 2024-05-24 CN disclosed
CN-118063786-A Novel MOF material and application thereof in lithium ion battery cathode 苏州芼孚士科技有限公司 2024-05-24 CN disclosed