Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503 | 0.89 | TSHR (0.52) | ALDH1A1TSHRHCAR2KMT2AMAPK1 | |
| Benzene SCHEMBL25178056 | 0.89 | TSHR (0.52) | ALDH1A1TSHRHCAR2KMT2AMAPK1 | |
| SCHEMBL901056 | 0.89 | TSHR (0.52) | ALDH1A1TSHRHCAR2KMT2AMAPK1 | |
| Benzyl Alcohol SCHEMBL8530567 | 0.89 | TSHR (0.52) | ALDH1A1TSHRHCAR2KMT2AMAPK1 | |
| Methylamine SCHEMBL27816806 | 0.88 | IDO1 (0.48) | ALDH1A1TSHRHCAR2KMT2AMAPK1 | |
| Methylamine SCHEMBL27600232 | 0.88 | IDO1 (0.48) | ALDH1A1TSHRHCAR2KMT2AMAPK1 | |
| Hydroxyamine SCHEMBL27588656 | 0.88 | ALDH1A1 (0.48) | ALDH1A1TSHRHCAR2KMT2AMAPK1 | |
| Propane SCHEMBL27744553 | 0.88 | TSHR (0.46) | ALDH1A1TSHRHCAR2KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL4378719 | 0.87 | TSHR (0.50) | ALDH1A1TSHRHCAR2KMT2AMAPK1 | |
| SCHEMBL4515729 | 0.87 | TSHR (0.50) | ALDH1A1TSHRHCAR2KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103074-A | Cytotoxic targeting chimeras for CCR2 expressing cells | 葛兰素史克知识产权发展有限公司 | 2024-05-28 | — | — | CN | disclosed |