Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25029977 | 1.00 | KMT2A (0.46) | KMT2ANPEPPSCA1CA2CA4 | |
| SCHEMBL31139900 | 1.00 | KMT2A (0.46) | KMT2ANPEPPSCA1CA2CA4 | |
| SCHEMBL29283299 | 1.00 | KMT2A (0.46) | KMT2ANPEPPSCA1CA2CA4 | |
| SCHEMBL31467338 | 1.00 | KMT2A (0.46) | KMT2ANPEPPSCA1CA2CA4 | |
| SCHEMBL5685793 | 0.90 | MEN1 (0.50) | KMT2ANPEPPSPOLBMEN1ITGB1 | |
| SCHEMBL25028402 | 0.90 | MEN1 (0.50) | KMT2ANPEPPSPOLBMEN1ITGB1 | |
| SCHEMBL10692607 | 0.85 | KMT2A (0.56) | KMT2ACA1CA2CA4CA7 | |
| SCHEMBL2637055 | 0.83 | ITGB1 (0.52) | KMT2ANPEPPSMEN1ITGB1ITGA4 | |
| SCHEMBL12549091 | 0.83 | ITGB1 (0.52) | KMT2ANPEPPSMEN1ITGB1ITGA4 | |
| SCHEMBL14003349 | 0.83 | ITGB1 (0.52) | KMT2ANPEPPSMEN1ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103074-A | Cytotoxic targeting chimeras for CCR2 expressing cells | 葛兰素史克知识产权发展有限公司 | 2024-05-28 | — | — | CN | disclosed |