Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028402 | 1.00 | MEN1 (0.50) | MEN1KMT2APOLBITGB1ITGA4 | |
| SCHEMBL29283299 | 0.90 | KMT2A (0.46) | MEN1KMT2APOLBITGB1ITGA4 | |
| SCHEMBL29283296 | 0.90 | KMT2A (0.46) | MEN1KMT2APOLBITGB1ITGA4 | |
| SCHEMBL25029977 | 0.90 | KMT2A (0.46) | MEN1KMT2APOLBITGB1ITGA4 | |
| SCHEMBL31139900 | 0.90 | KMT2A (0.46) | MEN1KMT2APOLBITGB1ITGA4 | |
| SCHEMBL31467338 | 0.90 | KMT2A (0.46) | MEN1KMT2APOLBITGB1ITGA4 | |
| SCHEMBL2637055 | 0.84 | ITGB1 (0.52) | MEN1KMT2AITGB1ITGA4NPSR1 | |
| SCHEMBL12549091 | 0.84 | ITGB1 (0.52) | MEN1KMT2AITGB1ITGA4NPSR1 | |
| SCHEMBL14003349 | 0.84 | ITGB1 (0.52) | MEN1KMT2AITGB1ITGA4NPSR1 | |
| SCHEMBL29283289 | 0.84 | ITGB1 (0.52) | MEN1KMT2AITGB1ITGA4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840895-B1 | METHODS OF OBTAINING RECEPTOR:RELEASE LIGAND (RELAND) COMPLEXES AND TEST ASSAYS | SEREX INC (US) | 2006-04-05 | — | — | EP | disclosed |
| EP-0840895-A4 | RECEPTOR:RELEASE LIGAND (RELAND) COMPLEXES AND ASSAYS AND KITS BASED THEREON | SEREX INC (US) | 2000-04-26 | — | — | EP | disclosed |
| EP-0600936-B1 | DIFFERENTIAL BINDING AFFINITIES AND DISSOCIATION ASSAYS BASED THEREON | SEREX INC (US) | 1999-10-06 | — | — | EP | disclosed |
| EP-0840895-A1 | RECEPTOR:RELEASE LIGAND (RELAND) COMPLEXES AND ASSAYS AND KITS BASED THEREON | SEREX, INC. (US) | 1998-05-13 | — | — | EP | disclosed |
| US-5710009-A | Receptor:release ligand (reland) complexes and release assays using said reland and methods and kits based thereon | SEREX, INC. (US) | 1998-01-20 | — | — | US | disclosed |
| WO-1997001097-A1 | RECEPTOR:RELEASE LIGAND (RELAND) COMPLEXES AND ASSAYS AND KITS BASED THEREON | SEREX, INC. (US) | 1997-01-09 | — | — | WO | disclosed |
| EP-0600936-A4 | DIFFERENTIAL BINDING AFFINITIES AND DISSOCIATION ASSAYS BASED THEREON. | SEREX INC (US) | 1996-08-28 | — | — | EP | disclosed |
| US-5527686-A | DETECTING COTININE BY CONTACT WITH RECEPTOR-LIGAND COMPLEX WHICH DISSOCIATES, RECEPTOR BINDING WITH COTININE; RELEASE ASSAY | SEREX, INC. (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0600936-A1 | DIFFERENTIAL BINDING AFFINITIES AND DISSOCIATION ASSAYS BASED THEREON | SEREX, INC. (US) | 1994-06-15 | — | — | EP | disclosed |
| WO-1993003367-A1 | DIFFERENTIAL BINDING AFFINITIES AND DISSOCIATION ASSAYS BASED THEREON | SEREX, INC. (US) | 1993-02-18 | — | — | WO | disclosed |