SCHEMBL29283306

SCHEMBL29283306

CCOC(=O)C1CCC(N2CCNCC2)CC1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.49
ALDH1A1 P00352 7/20 0.47
CHRM1 P11229 1/20 0.44
KMT2A Q03164 5/20 0.43
MEN1 O00255 3/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25028467 1.00 MAPT (0.49) MAPTALDH1A1CHRM1KMT2AMEN1
SCHEMBL2658539 0.88 MAPT (0.53) MAPTALDH1A1CHRM1KMT2AMEN1
Hydrochloric Acid SCHEMBL5026735 0.86 MAPT (0.51) MAPTALDH1A1CHRM1KMT2AMEN1
SCHEMBL3882849 0.85 MEN1 (0.55) MAPTALDH1A1CHRM1KMT2AMEN1
SCHEMBL8301383 0.84 MEN1 (0.57) MAPTALDH1A1CHRM1KMT2AMEN1
SCHEMBL2372673 0.84 MEN1 (0.57) MAPTALDH1A1CHRM1KMT2AMEN1
SCHEMBL28450924 0.83 MAPT (0.50) MAPTALDH1A1CHRM1KMT2AMEN1
SCHEMBL28443083 0.83 MAPT (0.50) MAPTALDH1A1CHRM1KMT2AMEN1
SCHEMBL28443081 0.83 MAPT (0.50) MAPTALDH1A1CHRM1KMT2AMEN1
SCHEMBL24837937 0.82 TP53 (0.45) ALDH1A1CHRM1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720044-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD Beactica Therapeutics AB (SE) 2026-04-08 EP disclosed
WO-2024240840-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD BEACTICA THERAPEUTICS AB (SE) 2024-11-28 WO disclosed
CN-118103074-A Cytotoxic targeting chimeras for CCR2 expressing cells 葛兰素史克知识产权发展有限公司 2024-05-28 CN disclosed