Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25030223 | 0.91 | EPHX1 (0.41) | EPHX1HRH3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20545129 | 0.89 | EPHX1 (0.46) | EPHX1HRH3SMN1; SMN2ACEMEN1 | |
| SCHEMBL25030226 | 0.83 | EPHX1 (0.41) | EPHX1HRH3MEN1KMT2ACACNA1H | |
| SCHEMBL16279606 | 0.81 | TDP1 (0.48) | EPHX1MEN1GAAKMT2ATDP1 | |
| SCHEMBL16279605 | 0.81 | TDP1 (0.48) | EPHX1MEN1GAAKMT2ATDP1 | |
| SCHEMBL8699456 | 0.81 | SMN1; SMN2 (0.44) | EPHX1SMN1; SMN2ACEMEN1GAA | |
| SCHEMBL18851365 | 0.79 | EPHX1 (0.46) | EPHX1HRH3SMN1; SMN2MEN1GAA | |
| SCHEMBL18851364 | 0.79 | EPHX1 (0.46) | EPHX1HRH3SMN1; SMN2MEN1GAA | |
| SCHEMBL7131093 | 0.78 | EPHX1 (0.45) | EPHX1HRH3SMN1; SMN2MEN1GAA | |
| SCHEMBL22151747 | 0.78 | EPHX1 (0.45) | EPHX1SMN1; SMN2MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103074-A | Cytotoxic targeting chimeras for CCR2 expressing cells | 葛兰素史克知识产权发展有限公司 | 2024-05-28 | — | — | CN | disclosed |