Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | DHPS | P49366 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31006556 | 1.00 | HSP90AB1 (0.51) | HSP90AB1ROCK2ROCK1DHPSHSD17B1 | |
| SCHEMBL29283816 | 0.90 | HSP90AB1 (0.53) | HSP90AB1ROCK2ROCK1DHPSHSD17B1 | |
| SCHEMBL31006529 | 0.90 | HSP90AB1 (0.53) | HSP90AB1ROCK2ROCK1DHPSHSD17B1 | |
| SCHEMBL29283795 | 0.90 | HSP90AB1 (0.57) | HSP90AB1ROCK2ROCK1DHPSGRM2 | |
| SCHEMBL31006516 | 0.90 | HSP90AB1 (0.57) | HSP90AB1ROCK2ROCK1DHPSGRM2 | |
| SCHEMBL29283813 | 0.88 | HSP90AB1 (0.67) | HSP90AB1ROCK2ROCK1HSD17B1HSD17B2 | |
| SCHEMBL31006547 | 0.88 | HSP90AB1 (0.67) | HSP90AB1ROCK2ROCK1HSD17B1HSD17B2 | |
| SCHEMBL31006536 | 0.85 | HSP90AB1 (0.51) | HSP90AB1ROCK2ROCK1DHPSCYP1A2 | |
| SCHEMBL29283796 | 0.85 | HSP90AB1 (0.51) | HSP90AB1ROCK2ROCK1DHPSCYP1A2 | |
| SCHEMBL24617273 | 0.83 | ROCK1 (0.50) | HSP90AB1ROCK2ROCK1DHPSHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184635-A | Quinolinone compound, pharmaceutical composition and application thereof | 安徽医科大学 | 2024-06-14 | — | — | CN | disclosed |