Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311363 | 0.94 | LMNA (0.44) | PRSS1PRSS2PRSS3LMNATSHR | |
| SCHEMBL1310747 | 0.88 | TSHR (0.41) | LMNATSHRHTR1AMAPT | |
| SCHEMBL28622222 | 0.88 | PRSS1 (0.48) | PRSS1PRSS2PRSS3LMNATSHR | |
| SCHEMBL27813140 | 0.87 | TSHR (0.42) | TSHRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL27776971 | 0.87 | TSHR (0.42) | TSHRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL27813191 | 0.86 | TSHR (0.44) | TSHRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL27833253 | 0.86 | TSHR (0.44) | TSHRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL27813184 | 0.86 | TSHR (0.44) | TSHRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL27980703 | 0.86 | TSHR (0.44) | TSHRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL27833312 | 0.86 | TSHR (0.44) | TSHRBIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2147909-A1 | METHOD FOR PRODUCTION OF ISOCYANATE USING COMPOSITION COMPRISING CARBAMIC ACID ESTER AND AROMATIC HYDROXY COMPOUND, AND COMPOSITION FOR TRANSPORT OR STORAGE OF CARBAMIC ACID ESTER | Asahi Kasei Chemicals Corporation (JP) | 2010-01-27 | — | — | EP | disclosed |