SCHEMBL29284253

SCHEMBL29284253

[CH2]CC(=CCCCC)CCCC

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.39
CA1 P00915 1/20 0.34
CES1 P23141 2/20 0.33
CES2 O00748 1/20 0.33
EP300 Q09472 1/20 0.33
F7 P08709 1/20 0.32
F3 P13726 1/20 0.32
FABP3 P05413 5/20 0.31
TP53 P04637 1/20 0.31
GRIK1 P39086 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29284278 0.91 EP300 (0.44) TSHREP300F7F3FABP3
SCHEMBL29284461 0.91 FABP3 (0.41) EP300F7F3FABP3TP53
SCHEMBL29284516 0.87 FABP3 (0.46) TSHREP300F7F3FABP3
SCHEMBL38749 0.85 ALDH1A1 (0.39) TSHRALDH1A1CA1CES1CES2
SCHEMBL16287422 0.84 TSHR (0.40) TSHRALDH1A1EP300GRIK1
SCHEMBL16287423 0.84 TSHR (0.40) TSHRALDH1A1EP300GRIK1
SCHEMBL28088662 0.83 ALDH1A1 (0.38) TSHRALDH1A1CA1CES1CES2
SCHEMBL29579491 0.83 ALDH1A1 (0.38) TSHRALDH1A1CA1CES1CES2
SCHEMBL29284374 0.83 EP300 (0.44) TSHREP300F7F3FABP3
SCHEMBL27563971 0.79 EP300 (0.43) TSHRALDH1A1CES1CES2EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed