Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.64 |
| ▸ | ITGAV | P06756 | 20/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.64 |
| ▸ | ITGB5 | P18084 | 8/20 | 0.64 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.48 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926952 | 1.00 | ITGB3 (0.64) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL2926296 | 0.95 | ITGB3 (0.64) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL2899798 | 0.94 | ITGB3 (0.63) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL2926893 | 0.94 | ITGB3 (0.72) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL2902160 | 0.94 | ITGB3 (0.72) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL2919048 | 0.93 | ITGB3 (0.61) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL2928843 | 0.93 | ITGB3 (0.61) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL2925244 | 0.89 | ITGB3 (0.72) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL2927247 | 0.89 | ITGB3 (0.71) | ITGB3ITGAVITGA2BITGB5ITGB6 | |
| SCHEMBL2902449 | 0.88 | ITGB3 (0.67) | ITGB3ITGAVITGA2BITGB5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217569-B1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | JANSSEN PHARMACEUTICA NV (BE) | 2014-04-16 | — | — | EP | disclosed |
| EP-2217569-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | Janssen Pharmaceutica N.V. (BE) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009058314-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |