Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20536139 | 0.81 | MEN1 (0.51) | MEN1KMT2ATDP1SMN1; SMN2HIF1A | |
| SCHEMBL30835243 | 0.74 | KMT2A (0.48) | MEN1KMT2ATDP1SMN1; SMN2HIF1A | |
| SCHEMBL27082578 | 0.74 | KMT2A (0.48) | MEN1KMT2ATDP1SMN1; SMN2HIF1A | |
| SCHEMBL22654320 | 0.68 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL30949870 | 0.68 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1L3MBTL1GAA | |
| SCHEMBL29882873 | 0.68 | MEN1 (0.56) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4651006 | 0.68 | APP (0.57) | KMT2ASLC22A12ALDH1A1GAA | |
| SCHEMBL28417549 | 0.68 | MEN1 (0.56) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4649684 | 0.68 | SLC22A12 (0.54) | KMT2ASLC22A12ALDH1A1GAA | |
| SCHEMBL18059677 | 0.68 | BRD4 (0.38) | MEN1KMT2ATDP1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |