Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24174014 | 1.00 | PDE4B (0.35) | PDE4BEPHX2EPHX1OPRK1NAMPT | |
| SCHEMBL22686919 | 1.00 | PDE4B (0.35) | PDE4BEPHX2EPHX1OPRK1NAMPT | |
| SCHEMBL29285159 | 0.90 | CYP4A11 (0.39) | PDE4BNAMPTCYP1A2QPCTQPCTL | |
| SCHEMBL20595095 | 0.90 | CYP4A11 (0.39) | PDE4BNAMPTCYP1A2QPCTQPCTL | |
| SCHEMBL29285147 | 0.90 | CYP4A11 (0.39) | PDE4BNAMPTCYP1A2QPCTQPCTL | |
| SCHEMBL1457027 | 0.89 | EPHX2 (0.40) | EPHX2EPHX1CYP1A2TDP1 | |
| SCHEMBL2679564 | 0.86 | TP53 (0.32) | TDP1 | |
| SCHEMBL344785 | 0.86 | TP53 (0.32) | TDP1 | |
| SCHEMBL1998545 | 0.86 | TP53 (0.32) | TDP1 | |
| SCHEMBL6499149 | 0.83 | CHRNB2 (0.39) | PDE4BEPHX1PIK3CDCHRNB2CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964643-B | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117964643-A | Pyrrole [2,3-b ] pyridine derivative and preparation method and application thereof | 苏州朗睿生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |