SCHEMBL29285258

SCHEMBL29285258

CC(=O)c1cc(Oc2ccc(C(=O)c3ccc(Oc4cc(C(C)=O)cc(C(C)=O)c4)cc3)cc2)cc(C(C)=O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.67
MAPT P10636 2/20 0.67
RAB9A P51151 2/20 0.67
SRD5A2 P31213 3/20 0.52
ESRRA P11474 1/20 0.49
POLB P06746 1/20 0.47
ELANE P08246 1/20 0.47
F2 P00734 1/20 0.46
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
ST14 Q9Y5Y6 1/20 0.46
ALDH1A1 P00352 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
HTT P42858 2/20 0.46
TSHR P16473 1/20 0.46
PARP15 Q460N3 2/20 0.45
PARP14 Q460N5 2/20 0.45
PARP10 Q53GL7 2/20 0.45
KMT2A Q03164 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17263308 0.87 MAPT (0.60) HPGDMAPTRAB9ASRD5A2ESRRA
SCHEMBL14017418 0.85 MAPT (0.61) HPGDMAPTRAB9AESRRAPOLB
SCHEMBL12799179 0.81 TUBB4A (0.60) HPGDMAPTRAB9ASRD5A2ALDH1A1
SCHEMBL20312254 0.81 SRD5A2 (0.62) HPGDMAPTRAB9ASRD5A2POLB
SCHEMBL203697 0.81 HPGD (1.00) HPGDMAPTRAB9AESRRAPOLB
SCHEMBL3301210 0.81 HPGD (1.00) HPGDMAPTRAB9AESRRAPOLB
SCHEMBL12240715 0.81 MAPT (0.73) HPGDMAPTRAB9ASRD5A2POLB
SCHEMBL9999840 0.81 HPGD (0.73) HPGDMAPTRAB9ASRD5A2ESRRA
SCHEMBL21935080 0.81 MAPT (0.73) HPGDMAPTRAB9ASRD5A2POLB
SCHEMBL21935942 0.81 MAPT (0.73) HPGDMAPTRAB9ASRD5A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118276403-A Photoresist underlayer composition and method of forming electronic device 罗门哈斯电子材料有限责任公司 2024-07-02 CN disclosed