SCHEMBL29285304

SCHEMBL29285304

CO[Si](CCCN)(OC)OC.[SiH3]CCCOCC1CO1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
ALDH1A1 P00352 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27930082 0.87 TSHR (0.42) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL28414446 0.84 SMN1; SMN2 (0.46) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL2868193 0.84 SMN1; SMN2 (0.46) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL5958589 0.83 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL10877779 0.83 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL27615 0.83 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL284717 0.83 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL30018303 0.83 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
Ethylenediamine SCHEMBL1129402 0.83 SMN1; SMN2 (0.56) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL11691876 0.82 TSHR (0.55) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290924-A Organic silicon foaming material and preparation method thereof 万华化学集团股份有限公司 2024-07-05 CN claimed