Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.52 |
| ▸ | REN | P00797 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PEPD | P12955 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29286222 | 1.00 | ACE (0.52) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL31290543 | 0.82 | XIAP (0.53) | — | |
| SCHEMBL31072125 | 0.81 | FKBP1A (0.54) | ACE | |
| SCHEMBL25132999 | 0.81 | FKBP1A (0.54) | ACE | |
| SCHEMBL31365829 | 0.81 | FKBP1A (0.54) | ACE | |
| SCHEMBL23795534 | 0.81 | ACE (0.55) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL28611939 | 0.81 | ACE (0.55) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL23795536 | 0.81 | ACE (0.55) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL757253 | 0.81 | ACE (0.68) | ACERENLMNAHSD17B10KDM4E | |
| SCHEMBL757254 | 0.81 | ACE (0.68) | ACERENLMNAHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118354796-A | Compounds, pharmaceutical compositions and methods for treating, preventing or managing hyperproliferative disorders | 文赛克斯制药有限责任公司 | 2024-07-16 | — | — | CN | disclosed |