Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29286535 | 0.86 | DHODH (0.44) | L3MBTL1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10362705 | 0.75 | MAPT (0.43) | L3MBTL1ALDH1A1KDM4ECYP3A4SMN1; SMN2 | |
| SCHEMBL19330152 | 0.74 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1KDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL7487026 | 0.72 | KDM4E (0.68) | L3MBTL1ALDH1A1KDM4ETDP1NPSR1 | |
| SCHEMBL9340558 | 0.71 | HSD17B10 (0.63) | ALDH1A1KDM4ECYP1A2ATMTDP1 | |
| SCHEMBL10361421 | 0.71 | MAPT (0.47) | L3MBTL1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL6560149 | 0.71 | KDM4E (0.51) | L3MBTL1ALDH1A1KDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL6559464 | 0.71 | ALDH1A1 (0.51) | L3MBTL1ALDH1A1KDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL6577826 | 0.70 | KDM4E (0.50) | ALDH1A1KDM4ECYP1A2ATMTDP1 | |
| SCHEMBL7236957 | 0.70 | MAPT (0.50) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272278-A | Substituted pyridine carboxylic acids, process for their preparation and compositions containing them | 因西利亚治疗私人有限公司 | 2021-08-17 | — | — | CN | disclosed |