SCHEMBL29286573

SCHEMBL29286573

CCC(=O)OC=C(C)C(=O)OCCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.46
TDP1 Q9NUW8 2/20 0.44
AKR1B10 O60218 3/20 0.43
AKR1B1 P15121 3/20 0.43
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
ALOX5 P09917 3/20 0.41
CTSK P43235 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ALDH1A1 P00352 2/20 0.40
TP53 P04637 1/20 0.40
GLA P06280 1/20 0.40
CYP3A4 P08684 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HIF1A Q16665 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL28726098 0.81 HCAR2 (0.49) HCAR2TDP1AKR1B10AKR1B1ESR1
SCHEMBL873497 0.81 HCAR2 (0.54) HCAR2TDP1AKR1B10AKR1B1ESR1
SCHEMBL872898 0.81 HCAR2 (0.54) HCAR2TDP1AKR1B10AKR1B1ESR1
SCHEMBL872900 0.81 HCAR2 (0.54) HCAR2TDP1AKR1B10AKR1B1ESR1
SCHEMBL28363851 0.80 HCAR2 (0.50) HCAR2TDP1AKR1B10AKR1B1ESR1
SCHEMBL6490850 0.79 HCAR2 (0.47) HCAR2TDP1AKR1B10AKR1B1ESR1
Phenethyl Propionate SCHEMBL4653082 0.79 TDP1 (0.59) HCAR2TDP1AKR1B10AKR1B1ESR1
Phenethyl Propionate SCHEMBL114088 0.78 TDP1 (0.63) HCAR2TDP1AKR1B10AKR1B1ESR1
SCHEMBL3292422 0.78 AKR1B10 (0.53) HCAR2TDP1AKR1B10AKR1B1ESR1
SCHEMBL28186332 0.77 HCAR2 (0.50) HCAR2TDP1AKR1B10AKR1B1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113278210-A Rubber-plastic alloy for modified asphalt mixture and preparation method thereof 山东高速集团有限公司创新研究院 2021-08-20 CN disclosed