Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 11/20 | 0.47 |
| ▸ | EYA3 | Q99504 | 6/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.44 |
| ▸ | TTR | P02766 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28104485 | 0.88 | CYP2C19 (0.59) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL28835165 | 0.87 | CYP2C19 (0.57) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL29286590 | 0.86 | SLC22A12 (0.49) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL28104494 | 0.86 | TTR (0.59) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL29286591 | 0.86 | SLC22A12 (0.63) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL28104784 | 0.83 | SLC22A12 (0.54) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL28104520 | 0.78 | SLC22A12 (0.51) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL29286599 | 0.77 | EYA3 (0.70) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL1287381 | 0.77 | SLC22A12 (0.78) | SLC22A12EYA3CYP2C9TTRCYP2C19 | |
| SCHEMBL29286594 | 0.77 | EYA3 (0.70) | SLC22A12EYA3CYP2C9TTRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106065010-B | For treating or preventing the compound of hyperuricemia or gout | 镇江新元素医药科技有限公司 | 2019-01-01 | — | — | CN | disclosed |