Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 2/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 3/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | PRKACA | P17612 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29286701 | 0.84 | AXL (0.46) | CCNB2CDK1CCNB1CCNB3RET | |
| SCHEMBL28061033 | 0.83 | IDO1 (0.56) | IDO1DYRK1AMAP2K1FGFR1FGFR4 | |
| SCHEMBL858484 | 0.82 | TUBB4A (0.57) | CCNB2CDK1CCNB1CCNB3CDC7 | |
| SCHEMBL29286697 | 0.81 | DYRK1A (0.45) | IDO1CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL857324 | 0.78 | AXL (0.49) | CDC7ROCK2PIM1PRKACACDK2 | |
| SCHEMBL31397692 | 0.77 | IDO1 (0.70) | IDO1RHEBTUBB4ATUBBTUBA3C | |
| SCHEMBL7712274 | 0.75 | RHEB (0.59) | IDO1CDC7PIM1PRKACAGSK3B | |
| SCHEMBL22802293 | 0.75 | AXL (0.54) | CDC7ROCK2PIM1PRKACACDK2 | |
| SCHEMBL3885714 | 0.75 | CDC7 (0.47) | CDK1CCNB1CDC7ROCK2PIM1 | |
| SCHEMBL11612594 | 0.74 | AXL (0.55) | CDC7ROCK2PIM1PRKACACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369645-B | Base-catalyzed green synthesis method of 3-arylthio-7-azaindole compound | 西北大学 | 2021-08-24 | — | — | CN | disclosed |