Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29287087 | 0.84 | NPC1 (0.47) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18796013 | 0.81 | HTT (0.60) | MAPTTDP1HPGDL3MBTL1NPC1 | |
| SCHEMBL29287094 | 0.77 | NQO2 (0.46) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL18796236 | 0.76 | NQO2 (0.44) | MAPTTDP1HPGDL3MBTL1NPC1 | |
| SCHEMBL27666105 | 0.74 | SMN1; SMN2 (0.61) | MAPTHPGDL3MBTL1NPC1RAB9A | |
| SCHEMBL12386818 | 0.74 | HTT (0.63) | MAPTHPGDL3MBTL1NPC1RAB9A | |
| SCHEMBL27645181 | 0.74 | MAP4K4 (0.53) | MAPTTDP1HPGDL3MBTL1NPC1 | |
| SCHEMBL30811086 | 0.73 | TDP1 (0.58) | MAPTTDP1HPGDL3MBTL1NPC1 | |
| SCHEMBL2400792 | 0.73 | TDP1 (0.58) | MAPTTDP1HPGDL3MBTL1NPC1 | |
| SCHEMBL31498821 | 0.73 | NCF1 (0.50) | MAPTHPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256451-B | Synthetic method of benzofuro [2,3-b ] quinoline derivative | 河南省科学院化学研究所有限公司 | 2021-09-03 | — | — | CN | disclosed |