Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.78 |
| ▸ | MAOA | P21397 | 14/20 | 0.78 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.58 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.58 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.56 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29288203 | 1.00 | MAOB (0.78) | MAOBMAOASPHK1S1PR1S1PR5 | |
| SCHEMBL6167500 | 0.94 | MAOB (0.79) | MAOBMAOASPHK1S1PR1S1PR5 | |
| SCHEMBL6167507 | 0.94 | MAOB (0.79) | MAOBMAOASPHK1S1PR1S1PR5 | |
| SCHEMBL6171245 | 0.93 | MAOB (0.74) | MAOBMAOASPHK1S1PR1S1PR5 | |
| SCHEMBL6171239 | 0.93 | MAOB (0.74) | MAOBMAOASPHK1S1PR1S1PR5 | |
| SCHEMBL29288235 | 0.88 | MAOB (0.77) | MAOBMAOASPHK1SCN3A | |
| SCHEMBL29288207 | 0.88 | MAOB (0.77) | MAOBMAOASPHK1SCN3A | |
| SCHEMBL29288210 | 0.88 | MAOB (1.00) | MAOBMAOASPHK1SCN3A | |
| SCHEMBL29288205 | 0.88 | MAOB (0.77) | MAOBMAOASPHK1SCN3A | |
| SCHEMBL29288236 | 0.88 | MAOB (0.77) | MAOBMAOASPHK1SCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912029-B | Nitrogen-containing heterocyclic amide derivative and use thereof | 广东东阳光药业有限公司 | 2021-10-01 | — | — | CN | disclosed |