Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.65 |
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.45 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29288191 | 0.88 | S1PR5 (0.50) | S1PR5S1PR1MAOBPDGFRAHTR2A | |
| SCHEMBL29288219 | 0.87 | HRH3 (0.52) | S1PR5S1PR1MAOBHTR2AKCNH2 | |
| SCHEMBL29288202 | 0.81 | HRH3 (0.53) | S1PR5S1PR1MAOBRXRARXRB | |
| SCHEMBL3042052 | 0.79 | S1PR5 (1.00) | S1PR5S1PR1MAOBRXRARXRB | |
| SCHEMBL23004599 | 0.79 | MAOB (0.53) | S1PR5S1PR1MAOBGID4RXRA | |
| SCHEMBL29288173 | 0.78 | S1PR5 (0.81) | S1PR5S1PR1MAOBRXRARXRB | |
| SCHEMBL3044721 | 0.76 | MAOB (0.64) | S1PR5S1PR1MAOBRXRARXRB | |
| SCHEMBL21347483 | 0.76 | HRH3 (0.68) | S1PR5S1PR1MAOBRXRARXRB | |
| SCHEMBL28115794 | 0.75 | MAOB (0.69) | S1PR5S1PR1MAOBGID4RXRA | |
| SCHEMBL3423658 | 0.72 | MAOB (0.65) | MAOBGID4RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912029-B | Nitrogen-containing heterocyclic amide derivative and use thereof | 广东东阳光药业有限公司 | 2021-10-01 | — | — | CN | disclosed |