Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29288219 | 0.89 | HRH3 (0.52) | HRH3S1PR5APPFAAHMAOB | |
| SCHEMBL29288191 | 0.87 | S1PR5 (0.50) | S1PR5FAAHCA12CA9MAOB | |
| SCHEMBL29288229 | 0.81 | S1PR5 (0.65) | S1PR5RXRARXRBMAOBS1PR1 | |
| SCHEMBL3041024 | 0.77 | S1PR5 (0.81) | HRH3S1PR5RXRARXRBS1PR1 | |
| SCHEMBL29288192 | 0.76 | MAOB (0.66) | HRH3S1PR5RXRARXRBMAOB | |
| SCHEMBL4591941 | 0.74 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL6057451 | 0.74 | HRH3 (0.82) | HRH3 | |
| SCHEMBL3038005 | 0.74 | HRH3 (0.77) | HRH3 | |
| SCHEMBL19946503 | 0.71 | APP (0.56) | APPRXRARXRBCA12CA1 | |
| SCHEMBL2399080 | 0.71 | APP (0.80) | APPRXRARXRBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912029-B | Nitrogen-containing heterocyclic amide derivative and use thereof | 广东东阳光药业有限公司 | 2021-10-01 | — | — | CN | disclosed |