Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.38 |
| ▸ | PGR | P06401 | 9/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 9/20 | 0.38 |
| ▸ | PPARG | P37231 | 8/20 | 0.38 |
| ▸ | PPARA | Q07869 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL292884 | 1.00 | NR3C1 (0.38) | NR3C1PGRNR3C2PPARGPPARA | |
| SCHEMBL292887 | 0.82 | PPARG (0.39) | NR3C1PGRNR3C2PPARGPPARA | |
| SCHEMBL292886 | 0.82 | NR3C1 (0.45) | NR3C1PGRNR3C2PPARGPPARA | |
| SCHEMBL675882 | 0.78 | NR3C1 (0.66) | NR3C1PGRNR3C2PPARGPPARA | |
| SCHEMBL13754566 | 0.78 | NR3C1 (0.66) | NR3C1PGRNR3C2PPARGPPARA | |
| SCHEMBL447350 | 0.78 | NR3C1 (0.66) | NR3C1PGRNR3C2PPARGPPARA | |
| SCHEMBL290769 | 0.66 | NR3C1 (0.68) | NR3C1PGRNR3C2 | |
| SCHEMBL13754567 | 0.66 | NR3C1 (0.68) | NR3C1PGRNR3C2 | |
| SCHEMBL290770 | 0.66 | NR3C1 (0.68) | NR3C1PGRNR3C2 | |
| SCHEMBL6807531 | 0.66 | NR3C1 (0.41) | NR3C1PGRNR3C2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049112-B1 | TREATING INFECTIONS AND SEQUELAE THEREOF WITH COMBINED DISSOCIATED GLUCOCORTICOID RECEPTOR AGONISTS AND ANTI-INFECTIVE AGENTS | BAUSCH & LOMB (US) | 2012-03-14 | — | — | EP | disclosed |