Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31110571 | 0.91 | L3MBTL1 (0.68) | L3MBTL1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL7283224 | 0.91 | L3MBTL1 (0.68) | L3MBTL1LMNAMAPTKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL8728483 | 0.90 | L3MBTL1 (0.66) | L3MBTL1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL24064576 | 0.83 | L3MBTL1 (0.61) | L3MBTL1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL7282911 | 0.82 | L3MBTL1 (0.73) | L3MBTL1LMNAMAPTKMT2ATDP1 | |
| Trifluoroacetic Acid SCHEMBL28251854 | 0.82 | L3MBTL1 (0.57) | L3MBTL1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL30556174 | 0.82 | L3MBTL1 (0.76) | L3MBTL1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL25009812 | 0.82 | L3MBTL1 (0.76) | L3MBTL1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL28836186 | 0.79 | L3MBTL1 (0.68) | L3MBTL1LMNAMAPTKMT2ATDP1 | |
| SCHEMBL25009811 | 0.79 | L3MBTL1 (0.82) | L3MBTL1LMNAMAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122031423-A | Composition containing nicorandil multi-piece structure for stepwise gentle sustained and controlled release drug delivery | 迈迪欣生物医药科技(西安)有限公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-115950213-A | Nicorandil for injection and freeze-drying method thereof | 福州华为医药技术开发有限公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-113599353-B | Preparation method of nicorandil for injection | 天津天士力之骄药业有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-113599353-A | Preparation method of nicorandil for injection | 天津天士力之骄药业有限公司 | 2021-11-05 | — | — | CN | disclosed |