Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989211 | 1.00 | TDP1 (0.62) | TDP1MAPTMEN1POLBKMT2A | |
| SCHEMBL1601620 | 0.91 | ALDH1A1 (0.53) | TDP1MAPTMEN1POLBKMT2A | |
| SCHEMBL7811089 | 0.88 | POLB (0.63) | TDP1MAPTMEN1POLBKMT2A | |
| SCHEMBL12798874 | 0.88 | TDP1 (0.62) | TDP1MAPTMEN1POLBKMT2A | |
| SCHEMBL11079242 | 0.86 | TDP1 (0.60) | TDP1MAPTMEN1POLBKMT2A | |
| SCHEMBL31423774 | 0.86 | TDP1 (0.60) | TDP1MAPTMEN1POLBKMT2A | |
| SCHEMBL16655546 | 0.85 | TDP1 (0.58) | TDP1MAPTMEN1POLBKMT2A | |
| SCHEMBL1069671 | 0.85 | TSHR (0.59) | TDP1MAPTMEN1POLBKMT2A | |
| SCHEMBL4588943 | 0.85 | TDP1 (0.58) | TDP1MAPTMEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL7368798 | 0.85 | TDP1 (0.58) | TDP1MAPTMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047591-A | Single-stage process for producing bis-(amino-nitrophenyl)-methane | CIBA-GEIGY CORPORATION (US) | 1991-09-10 | — | — | US | claimed |
| EP-2044136-B1 | POLYUREA-POLYURETHANE MOLDINGS AND PROCESS FOR THEIR PRODUCTION | BAYER MATERIALSCIENCE AG (DE) | 2010-09-15 | — | — | EP | disclosed |
| EP-2044136-A1 | POLYUREA-POLYURETHANE MOLDINGS AND PROCESS FOR THEIR PRODUCTION | Bayer MaterialScience AG (DE) | 2009-04-08 | — | — | EP | disclosed |
| US-20080015311-A1 | Polyurea-polyurethane molded articles and process for their production | BAYER MATERIALSCIENCE AG (DE) | 2008-01-17 | — | — | US | disclosed |
| WO-2008006472-A1 | POLYUREA-POLYURETHANE MOLDINGS AND PROCESS FOR THEIR PRODUCTION | BAYER MATERIALSCIENCE AG (DE) | 2008-01-17 | — | — | WO | disclosed |
| EP-0573873-B1 | Process for the preparation of urethane or urea groups-containing compact or cellular elastomers or mouldings thereof | BASF AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| EP-0573867-B1 | Process for the preparation of urethane or urethane and urea groups-containing elastomers by using N-perethoxylated polyoxyalkylene-polyamines as reactive components | BASF AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| EP-0438695-B1 | Process for the preparation of elastic compact or cellular moulded articles on the basis of elastomers containing N-benzylurea groups, such elastomers and N-benzyl-polyoxyalkylene-polyamines suitable therefor | BASF AG (DE) | 1995-09-20 | — | — | EP | disclosed |
| US-5364852-A | Molding materials | BASF AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| EP-0438696-B1 | Process for the preparation of elastic compact or cellular moulded articles on the basis of elastomers containing N-substituted urea- and amide groups, such elastomers and polyoxyalkylene-polyamine mixtures, containing polyazomethines, suitable therefor | BASF AG (DE) | 1994-11-02 | — | — | EP | disclosed |
| US-4789691-A | REACTING POLYISOCYANATE, POLYAZOMETHINE, AND AROMATIC POLYAMINES | BASF AKTIENGESELLSCHAFT (DE) | 1988-12-06 | — | — | US | disclosed |
| EP-0157119-B1 | PROCESS FOR THE PREPARATION OF OPTIONALLY CELLULAR POLYURETHANE-POLYUREA MOULDED OBJECTS | BASF Aktiengesellschaft (DE) | 1987-09-30 | — | — | EP | disclosed |
| US-4636531-A | REACTION INJECTION MOLDING, CHAIN EXTENSION, STERIC HINDRANCE, PRIMARY AROMATIC DIAMINE | BASF AKTIENGESELLSCHAFT (DE) | 1987-01-13 | — | — | US | disclosed |
| US-4595705-A | Using as polyol 95 to 60 percent conventional polyol and 5 to 40 percent aromatic polyester polyol | BASF AKTIENGESELLSCHAFT (DE) | 1986-06-17 | — | — | US | disclosed |
| EP-0180758-A1 | Process for the preparation of optionally cellular moulded bodies of polyurethane-polyurea by using 2,4 and/or 2,6 tolylene diisocyanates containing urethane and isocyanurate groups | BASF Aktiengesellschaft (DE) | 1986-05-14 | — | — | EP | disclosed |
| EP-0157119-A1 | Process for the preparation of optionally cellular polyurethane-polyurea moulded objects | BASF Aktiengesellschaft (DE) | 1985-10-09 | — | — | EP | disclosed |
| EP-0157120-A1 | Process for the preparation of optionally cellular polyurethane-polyurea moulded objects having demoulding properties | BASF Aktiengesellschaft (DE) | 1985-10-09 | — | — | EP | disclosed |
| EP-0069286-B1 | PROCESS FOR THE PRODUCTION OF POSSIBLY CELLULAR POLYURETHANE POLYUREA MOULDED ARTICLES, AND ALKYL- SUBSTITUTED PHENYLENE DIAMINES FOR THAT PURPOSE | BASF Aktiengesellschaft (DE) | 1985-09-18 | — | — | EP | disclosed |
| EP-0109624-A2 | Process for producing shaped articles made from polyurethane-polyurea which may be cellular | BASF Aktiengesellschaft (DE) | 1984-05-30 | — | — | EP | disclosed |
| EP-0026915-A2 | Process for preparing moulded polyurethane-polyurea articles which may contain cells | BASF Aktiengesellschaft (DE) | 1981-04-15 | — | — | EP | disclosed |