SCHEMBL29290485

SCHEMBL29290485

COC(=O)c1ccc(S(=O)(=O)O)cc1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
HSD17B10 Q99714 4/20 0.56
HPGD P15428 3/20 0.56
KDM4E B2RXH2 3/20 0.56
GAA P10253 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
S1PR3 Q99500 1/20 0.49
TSHR P16473 2/20 0.43
POLB P06746 2/20 0.43
APEX1 P27695 1/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CA2 P00918 4/20 0.43
LMNA P02545 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA7 P43166 1/20 0.42
PDK2 Q15119 1/20 0.42
PDK4 Q16654 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28582979 0.98 ALDH1A1 (0.54) ALDH1A1HSD17B10HPGDKDM4EGAA
SCHEMBL27747650 0.93 ALDH1A1 (0.56) ALDH1A1HSD17B10HPGDKDM4EGAA
SCHEMBL31083420 0.91 ALDH1A1 (0.47) ALDH1A1HSD17B10HPGDKDM4EGAA
SCHEMBL5861459 0.91 ALDH1A1 (0.47) ALDH1A1HSD17B10HPGDKDM4EGAA
SCHEMBL270431 0.91 ALDH1A1 (0.47) ALDH1A1HSD17B10HPGDKDM4EGAA
SCHEMBL5861451 0.90 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDKDM4EGAA
SCHEMBL11575404 0.88 POLB (0.55) ALDH1A1HSD17B10HPGDKDM4EGAA
SCHEMBL11574049 0.85 POLB (0.56) ALDH1A1HSD17B10KDM4EGAAMEN1
Methyl Alcohol SCHEMBL28948585 0.84 HSD17B10 (0.65) ALDH1A1HSD17B10HPGDKDM4EMEN1
SCHEMBL61251 0.84 HSD17B10 (0.69) ALDH1A1HSD17B10HPGDKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109608366-A A kind of production method for improving the synthesis of three monomers and using dimethyl isophthalate -5- sulfonic acid yield and purity 泰山医学院 2019-04-12 CN disclosed