SCHEMBL2929068

SCHEMBL2929068

CCCC(N)n1ccnc1

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 10/20 0.46
CYP19A1 P11511 7/20 0.39
TBXAS1 P24557 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28362531 0.96 CYP17A1 (0.44) CYP17A1CYP19A1TBXAS1
SCHEMBL4374035 0.89 CYP17A1 (0.49) CYP17A1CYP19A1TBXAS1
SCHEMBL10770402 0.87 CYP17A1 (0.44) CYP17A1CYP19A1TBXAS1
SCHEMBL28650976 0.85 TBXAS1 (0.47) CYP17A1CYP19A1TBXAS1
SCHEMBL28227574 0.85 TBXAS1 (0.47) CYP17A1CYP19A1TBXAS1
SCHEMBL72311 0.83
Hydrochloric Acid SCHEMBL9020718 0.82 CYP17A1 (0.42) CYP17A1CYP19A1
SCHEMBL7073676 0.80 CYP17A1 (0.37) CYP17A1CYP19A1TBXAS1
SCHEMBL16163611 0.79 CYP17A1 (0.49) CYP17A1CYP19A1TBXAS1
SCHEMBL5328653 0.79 CYP17A1 (0.49) CYP17A1CYP19A1TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0848053-B1 Mixtures of esterified carboxy-containing interpolymers and lubricants containing them LUBRIZOL CORP (US) 2010-09-29 EP disclosed
EP-1200541-B1 NITROGEN-CONTAINING ESTERIFIED CARBOXY-CONTAINING INTERPOLYMERS HAVING ENHANCED OXIDATIVE STABILITY AND LUBRICANTS CONTAINING THEM LUBRIZOL CORP (US) 2010-02-10 EP disclosed
EP-0853115-B1 Additive concentrates containing mixtures of organic diluents and esterified carboxy-containing interpolymers and lubricants containing them LUBRIZOL CORP (US) 2004-11-17 EP disclosed
US-6544935-B1 Useful as viscosity improvers THE LUBRIZOL CORPORATION 2003-04-08 US disclosed
EP-1200541-A1 NITROGEN-CONTAINING ESTERIFIED CARBOXY-CONTAINING INTERPOLYMERS HAVING ENHANCED OXIDATIVE STABILITY AND LUBRICANTS CONTAINING THEM The Lubrizol Corporation (US) 2002-05-02 EP disclosed
WO-2001004242-A1 NITROGEN-CONTAINING ESTERIFIED CARBOXY-CONTAINING INTERPOLYMERS HAVING ENHANCED OXIDATIVE STABILITY AND LUBRICANTS CONTAINING THEM THE LUBRIZOL CORPORATION (US) 2001-01-18 WO disclosed
US-5880074-A ADDITIVE CONCENTRATE COMPRISING DILUENT SELECTED FROM SYNTHETIC OIL OR NAPHTHENIC OILS, AN ESTER DERIVED FROM A CARBOXY-CONTAINING INTERPOLYMER HAVING REDUCED SPECIFIC VISCOSITY; GOOD LOW TEMPERATURE CHARACTERISTICS LUBRIZOL CORPORATION THE 1999-03-09 US disclosed
EP-0853115-A1 Additive concentrates containing mixtures of organic diluents and esterified carboxy-containing interpolymers and lubricants containing them The Lubrizol Corporation (US) 1998-07-15 EP disclosed
EP-0848053-A1 Mixtures of esterified carboxy-containing interpolymers and lubricants containing them The Lubrizol Corporation (US) 1998-06-17 EP disclosed
CN-1113493-A Boron containing derivative and preparation and medical application of same SYNTHELABO (FR) 1995-12-20 CN disclosed
US-5283235-A Drilling and wqell completin fluids of a water in oil emulsion comprising a mixture of a brine, liquid hydrocarbon and a alpha-olefin or vinyl aromatic/acrylic acid or anhydride modified by a fatty alcohol THE LUBRIZOL CORPORATION (US) 1994-02-01 US disclosed
EP-0561608-A2 Compositions containing esters of carboxy-containing interpolymers and methods of using the same THE LUBRIZOL CORPORATION (US) 1993-09-22 EP disclosed
EP-0188999-B1 CATIONIC REACTION PRODUCTS FROM 1-AMINOALKYL IMIDAZOLE COMPOUNDS AND EPIHALOGEN HYDRINS CIBA-GEIGY AG (CH) 1989-05-31 EP disclosed
US-4705865-A Cationic reaction products formed from 1-aminoalkyl-imidazole compounds and epihalohydrins CIBA-GEIGY CORPORATION (US) 1987-11-10 US disclosed
EP-0188999-A1 Cationic reaction products from 1-aminoalkyl imidazole compounds and epihalogen hydrins CIBA-GEIGY AG (CH) 1986-07-30 EP disclosed
US-4599336-A BRONCHODILATOR, THROMBOXANE SYNTHETASE INHIBITOR, ANTIARRHYTHMIA HOFFMANN-LA ROCHE INC. (US) 1986-07-08 US disclosed
US-4551460-A ANTICOAGULANTS, CARDIOVASCULAR DISORDERS HOFFMANN-LA ROCHE INC. (US) 1985-11-05 US disclosed
EP-0142057-A2 Thiazoloquinazoline derivatives, their preparation and pharmaceutical compositions containing same F. HOFFMANN-LA ROCHE AG (CH) 1985-05-22 EP disclosed
EP-0094080-A2 Pyrido(2,1-b)quinazoline derivatives F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1983-11-16 EP disclosed