SCHEMBL29290758

SCHEMBL29290758

CCOCCOCCn1c(O)cc(C)c(C#N)c1=O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 13/20 0.50
USP2 O75604 1/20 0.50
LMNA P02545 3/20 0.49
KMT2A Q03164 7/20 0.44
MEN1 O00255 6/20 0.44
MAPT P10636 4/20 0.42
HPGD P15428 2/20 0.42
GAA P10253 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
THRB P10828 1/20 0.40
HSD17B10 Q99714 4/20 0.40
ALDH1A1 P00352 6/20 0.39
MAPK1 P28482 1/20 0.39
TSHR P16473 1/20 0.39
RAB9A P51151 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13927300 0.97 KDM4E (0.52) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL29290757 0.90 KDM4E (0.55) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL11133471 0.89 KDM4E (0.50) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL29290761 0.88 KDM4E (0.49) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL13758673 0.88 KDM4E (0.51) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL29290759 0.87 KDM4E (0.51) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL28543641 0.84 KDM4E (0.48) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL29290760 0.84 KDM4E (0.51) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL5365762 0.83 KDM4E (0.51) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL11200329 0.83 KDM4E (0.52) KDM4EUSP2LMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108250788-B Pyridone azo disperse dye containing sulfonate group and synthesis method thereof 江苏迪安化工有限公司 2021-11-16 CN disclosed