SCHEMBL11200329

SCHEMBL11200329

CCCOCCCn1c(O)cc(C)c(C#N)c1=O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 12/20 0.52
USP2 O75604 2/20 0.52
LMNA P02545 3/20 0.48
KMT2A Q03164 7/20 0.47
MEN1 O00255 6/20 0.47
MAPT P10636 4/20 0.47
HPGD P15428 1/20 0.41
THRB P10828 1/20 0.39
HSD17B10 Q99714 3/20 0.39
ALDH1A1 P00352 5/20 0.39
MAPK1 P28482 2/20 0.39
TSHR P16473 1/20 0.38
RAB9A P51151 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GAA P10253 2/20 0.38
GLA P06280 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
POLB P06746 1/20 0.36
UPP1 Q16831 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29290760 0.99 KDM4E (0.51) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL11132533 0.95 KDM4E (0.52) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL29290759 0.94 KDM4E (0.51) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL29290757 0.92 KDM4E (0.55) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL11133471 0.91 KDM4E (0.50) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL29290755 0.88 KDM4E (0.46) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL29290761 0.87 KDM4E (0.49) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL623429 0.86 KDM4E (0.60) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL2014331 0.85 KDM4E (0.50) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL11129423 0.85 KDM4E (0.59) KDM4EUSP2LMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108299289-B Pyridone azo disperse dye containing sulfonate group and synthesis method thereof 江苏迪安化工有限公司 2020-11-24 CN disclosed
EP-0091882-A1 Stable dyestuff, process for preparing it and its use in dyeing and printing synthetic and semi-synthetic fibres CIBA-GEIGY AG (CH) 1983-10-19 EP disclosed