Pyridine

Pyridine

SCHEMBL29290799

CNc1ccn(C)c1.c1ccncc1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.37
TSHR P16473 2/20 0.37
ACHE P22303 2/20 0.34
MAOA P21397 1/20 0.34
NAPRT Q6XQN6 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2E1 P05181 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2B6 P20813 1/20 0.31
CYP2C19 P33261 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2735994 0.84
Pyridine SCHEMBL28329116 0.73 TSHR (0.70) TSHRNAPRTTDP1GAA
Pyridine SCHEMBL28212748 0.72 PPARA (0.48) PPARATSHRACHEMAOATDP1
SCHEMBL21613918 0.71 TSHR (0.65) TSHRNAPRTTDP1CYP2C19GAA
Pyridine SCHEMBL28138233 0.68 TSHR (0.38) PPARATSHRNAPRTTDP1GAA
SCHEMBL24773512 0.67
Pyridine SCHEMBL28758817 0.67 TSHR (0.46) TSHRTDP1CYP2C19GAA
O-Xylene SCHEMBL27528375 0.67 TSHR (0.58) TSHRACHENAPRTTDP1CYP2C19
P-Xylene SCHEMBL27528373 0.67 TSHR (0.58) TSHRACHETDP1CYP2C9CYP2C19
Fluoride SCHEMBL29031926 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651388-A Parithenolide dithiocarbamate derivative and its salt, medical composition and its use 南开大学 2019-04-19 CN disclosed