Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.51 |
| ▸ | ITGB7 | P26010 | 15/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164190 | 0.91 | ITGB1 (0.61) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL2770094 | 0.90 | ITGB1 (0.51) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL2923131 | 0.90 | ITGB1 (0.49) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL4445947 | 0.87 | ITGB1 (0.55) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL4448585 | 0.82 | ITGB1 (0.59) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2769874 | 0.81 | ITGB1 (0.60) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL2769586 | 0.81 | ITGB1 (0.60) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL2770790 | 0.81 | ITGB1 (0.49) | ITGB1ITGA4ITGB7ITGAV | |
| Hydrochloric Acid SCHEMBL2769227 | 0.80 | ITGB1 (0.59) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL2769581 | 0.79 | ITGB1 (0.58) | ITGB1ITGA4ITGB7ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231185-A1 | METHODS AND COMPOSITIONS FOR TREATING LIQUID TUMORS | Elan Pharmaceuticals Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| EP-1635822-A4 | METHODS AND COMPOSITIONS FOR TREATING RHEUMATOID ARTHRITIS | ELAN PHARM INC (US) | 2009-06-24 | — | — | EP | disclosed |
| WO-2009075806-A1 | METHODS AND COMPOSITIONS FOR TREATING LIQUID TUMORS | ELAN PHARMACEUTICALS, INC. (US) | 2009-06-18 | — | — | WO | disclosed |
| EP-1507533-A4 | HETEROARYL COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY ALPHA-4 INTEGRINS | ELAN PHARM INC (US) | 2007-05-23 | — | — | EP | disclosed |
| EP-1635822-A2 | METHODS AND COMPOSITIONS FOR TREATING RHEUMATOID ARTHRITIS | Elan Pharmaceuticals, Inc. (US) | 2006-03-22 | — | — | EP | disclosed |
| EP-1507533-A2 | HETEROARYL COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY ALPHA-4 INTEGRINS | Elan Pharmaceuticals, Inc. (US) | 2005-02-23 | — | — | EP | disclosed |
| WO-2005000246-A2 | METHODS AND COMPOSITIONS FOR TREATING RHEUMATOID ARTHRITIS | ELAN PHARMACEUTICALS, INC. (US) | 2005-01-06 | — | — | WO | disclosed |
| WO-2003099231-A2 | HETEROARYL COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY ALPHA-4 INTEGRINS | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-04 | — | — | WO | disclosed |