Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.59 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.59 |
| ▸ | ITGB7 | P26010 | 11/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2929891 | 0.89 | ITGB1 (0.73) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2608695 | 0.88 | ITGB1 (0.59) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2768840 | 0.88 | ITGB1 (0.59) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5511419 | 0.87 | ITGB1 (0.56) | ITGB1ITGA4ITGB7 | |
| SCHEMBL4445947 | 0.82 | ITGB1 (0.55) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2929216 | 0.82 | ITGB1 (0.51) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2961386 | 0.78 | ITGB1 (0.51) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2608696 | 0.77 | ITGB1 (0.57) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2608698 | 0.76 | ITGB1 (0.56) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413165 | 0.76 | ITGB1 (0.70) | ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635822-A4 | METHODS AND COMPOSITIONS FOR TREATING RHEUMATOID ARTHRITIS | ELAN PHARM INC (US) | 2009-06-24 | — | — | EP | disclosed |
| EP-1635822-A2 | METHODS AND COMPOSITIONS FOR TREATING RHEUMATOID ARTHRITIS | Elan Pharmaceuticals, Inc. (US) | 2006-03-22 | — | — | EP | disclosed |
| WO-2005000246-A2 | METHODS AND COMPOSITIONS FOR TREATING RHEUMATOID ARTHRITIS | ELAN PHARMACEUTICALS, INC. (US) | 2005-01-06 | — | — | WO | disclosed |